Research Details

Transcriptomic and Histological Manifestations of Alcohol-Induced Damage and Repair Using Pomacea canaliculata Slime and Bovine Milk in ICR Mice (Mus Musculus) Digestive Tissues.

1. Dr. Doreen D. Domingo 2. Dr. Peter James I. Gann 3. Jessica G. Asuncion 4. Donna Mae Fronda

Category: Study

Status: On-going

Duration: February 1, 2025 - February 28, 2026

Expected Output

Product (P):
-        Comprehensive report on the molecular expression during alcohol-induced liver damage pathway in mice and its implications for future research and clinical application.
-        Development of possible therapeutic targets or strategies targeted at reducing alcohol-induced liver damage.
 
Publication (P):
-        Contribute to the advancement of alcohol-induced liver damage pathogenesis  through submission of the study results for publication in peer-reviewed scientific publications. 
-        Dissemination of the research findings at pertinent scientific conferences and symposiums and the establishment of linkage with other scientists and subject matter experts.
 
Policy (P):
-        Advocating for policies that raise knowledge about the harmful effects of alcohol intake on liver health and encourage preventive measures requires engaging with policymakers and key stakeholders through evidence-based recommendations.
 
People Services (P):
-        Provision of educational materials to inform the public, medical professionals, and policymakers on the hazards to liver health associated with alcohol consumption and early detection techniques. 
 
Places and Partnerships (P):
-        Partnering with academic institutions, research organizations, and healthcare facilities to foster interdisciplinary research endeavors and share specialized knowledge in the fields of liver pathogenesis and alcohol-related diseases
-        Collaboration with advocacy groups, community organizations and government agencies to support programs tackling the promotion of liver health and education against alcohol abuse.
 
Social Impact (I):
-        Improvement in the access to resources and services relevant to alcohol-related liver diseases among the general populace, which can further lead to positive changes in behavior and lifestyle.

Social Impact (I):
-        Improvement in the access to resources and services relevant to alcohol-related liver diseases among the general populace, which can further lead to positive changes in behavior and lifestyle.
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Economic Impact (I):
-        Provision of potential treatment and management of alcohol-related liver and stomach diseases at lower healthcare costs by employing preventive interventions and early detection strategies derived from the results of this study
Possible source of inspiration/mechanism for the development of novel therapeutic interventions or even diagnostic tools targeting the aspects of liver disease which were determined in this study - thereby promoting job creation and revenue generation for both the healthcare and pharmaceutical sectors.